Technological and Administrative Factors Implementing a Virtual Human Biospecimen Repository
نویسندگان
چکیده
The value of human biospecimens available for research dramatically increases when linked with their accumulated clinical and molecular (genomic, proteomic, subcellular modeling) data. Further, informatics tools make it possible for researchers (both intra- and inter-institutionally) to locate tissue needed for research faster and more reliably. We are developing a virtual human biospecimen repository to both inventory and link all human biospecimens with clinical and genomics data to optimize their value for research, while satisfying all privacy and human subjects protections regulations.
منابع مشابه
Towards a Common Informatics Framework for Biorepositories
Many biomedical research laboratories, departments and organizations struggle to manage data in biospecimen repositories that supply basic and translational research. Biorepository information systems have been developed from a variety of perspectives, and are often difficult to integrate or network within and across organizations due to lack of structural and semantic alignment with standards....
متن کاملStandard preanalytical coding for biospecimens: defining the sample PREanalytical code.
BACKGROUND Management and traceability of biospecimen preanalytical variations are necessary to provide effective and efficient interconnectivity and interoperability between Biobanks. METHODS Therefore, the International Society for Biological and Environmental Repositories Biospecimen Science Working Group developed a "Standard PREanalytical Code" (SPREC) that identifies the main preanalyti...
متن کاملProviding Contemporary Access to Historical Biospecimen Collections: Development of the NHLBI Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC)
The National Heart, Lung, and Blood Institute (NHLBI), within the United States' National Institutes of Health (NIH), established a Biorepository in 1976 that initially archived biospecimens from population-based blood product safety surveys. It was later expanded to biospecimens from clinical and epidemiological studies in heart, lung, and blood disorders. The NHLBI also established a Data Rep...
متن کاملHuman biospecimen research: experimental protocol and quality control tools.
Human Biospecimen Research: Experimental Protocol and Quality Control Tools. Fotini Betsou, Rebecca Barnes, Thomas Burke, Domenico Coppola, Yvonne DeSouza, James Eliason, Barbara Glazer, David Horsfall, Cynthia Kleeberger, Sylvain Lehmann, Anil Prasad, Amy Skubitz, Stella Somiari, and Elaine Gunter (International Society for Biological and Environmental Repositories (ISBER) Working Group on Bio...
متن کاملMulti-institutional tumor banking: lessons learned from a pancreatic cancer biospecimen repository.
Clinically annotated pancreatic cancer samples are needed for progress to be made toward developing more effective treatments for this deadly cancer. As part of a National Cancer Institute-funded program project, we established a biospecimen core to support the research efforts. This article summarizes the key hurdles encountered and solutions we found in the process of developing a successful ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- AMIA ... Annual Symposium proceedings. AMIA Symposium
دوره شماره
صفحات -
تاریخ انتشار 2005